Accurate genome relative abundance estimation based on shotgun metagenomic reads.

Accurate estimation of microbial community composition based on metagenomic sequencing data is fundamental for subsequent metagenomics analysis. Prevalent estimation methods are mainly based on directly summarizing alignment results or its variants; often result in biased and/or unstable estimates....

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Bibliographic Details
Main Authors: Li C Xia, Jacob A Cram, Ting Chen, Jed A Fuhrman, Fengzhu Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3232206?pdf=render