Molecular epidemiology and expression of capsular polysaccharides in Staphylococcus aureus clinical isolates in the United States.

Staphylococcus aureus capsular polysaccharides (CP) are important virulence factors under evaluation as vaccine antigens. Clinical S. aureus isolates have the biosynthetic capability to express either CP5 or CP8 and an understanding of the relationship between CP genotype/phenotype and S. aureus epi...

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Bibliographic Details
Main Authors: Naglaa Mohamed, Yekaterina Timofeyeva, Dorota Jamrozy, Eduardo Rojas, Li Hao, Natalie C Silmon de Monerri, Julio Hawkins, Guy Singh, Bing Cai, Paul Liberator, Shite Sebastian, Robert G K Donald, Ingrid L Scully, C Hal Jones, C Buddy Creech, Isaac Thomsen, Julian Parkhill, Sharon J Peacock, Kathrin U Jansen, Matthew T G Holden, Annaliesa S Anderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208356