On the Role of Calcium-Permeable AMPARs in Long-Term Potentiation and Synaptic Tagging in the Rodent Hippocampus

On the Role of Calcium-Permeable AMPARs in Long-Term Potentiation and Synaptic Tagging in the Rodent Hippocampus

Classically, long-term potentiation (LTP) at hippocampal CA1 synapses is triggered by the synaptic activation of NMDA receptors (NMDARs). More recently, it has been shown that calcium-permeable (CP)-AMPARs can also trigger synaptic plasticity at these synapses. Specifically, their activation is requ...

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Bibliographic Details
Main Authors: Pojeong Park, Heather Kang, Thomas M. Sanderson, Zuner A. Bortolotto, John Georgiou, Min Zhuo, Bong-Kiun Kaang, Graham L. Collingridge
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
NMDA receptor
long-term potentiation
hippocampus
calcium-permeable AMPA receptor
PKA
protein synthesis
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2019.00004/full

Internet

https://www.frontiersin.org/article/10.3389/fnsyn.2019.00004/full

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