Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury.

Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury.

Influenza virus A (IAV) causes annual epidemics and intermittent pandemics that affect millions of people worldwide. Potent inflammatory responses are commonly associated with severe cases of IAV infection. The complement system, an important mechanism of innate and humoral immune responses to infec...

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Bibliographic Details
Main Authors: Cristiana C Garcia, Wynne Weston-Davies, Remo C Russo, Luciana P Tavares, Milene A Rachid, José C Alves-Filho, Alexandre V Machado, Bernhard Ryffel, Miles A Nunn, Mauro M Teixeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3655967?pdf=render

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http://europepmc.org/articles/PMC3655967?pdf=render

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