Three-Dimensional Interactions Analysis of the Anticancer Target c-Src Kinase with Its Inhibitors

Src family kinases (SFKs) constitute the biggest family of non-receptor tyrosine kinases considered as therapeutic targets for cancer therapy. An aberrant expression and/or activation of the proto-oncogene c-Src kinase, which is the oldest and most studied member of the family, has long been demonst...

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Bibliographic Details
Main Authors: Vibhu Jha, Marco Macchia, Tiziano Tuccinardi, Giulio Poli
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/8/2327