FMRFamide-like peptides (FLPs) enhance voltage-gated calcium currents to elicit muscle contraction in the human parasite Schistosoma mansoni.

Schistosomes are amongst the most important and neglected pathogens in the world, and schistosomiasis control relies almost exclusively on a single drug. The neuromuscular system of schistosomes is fertile ground for therapeutic intervention, yet the details of physiological events involved in neuro...

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Bibliographic Details
Main Authors: Ekaterina Novozhilova, Michael J Kimber, Hai Qian, Paul McVeigh, Alan P Robertson, Mostafa Zamanian, Aaron G Maule, Tim A Day
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2919380?pdf=render