Sepsis induces specific changes in histone modification patterns in human monocytes.

Sepsis is a global burden and the primary cause of death in intensive care units worldwide. The pathophysiological changes induced by the host's systemic inflammatory response to infection are not yet fully understood. During sepsis, the immune system is confronted with a variety of factors, wh...

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Bibliographic Details
Main Authors: Sebastian Weiterer, Florian Uhle, Christoph Lichtenstern, Benedikt H Siegler, Sabin Bhuju, Michael Jarek, Marek Bartkuhn, Markus A Weigand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368631?pdf=render