Blocking of the High-Affinity Interaction-Synapse Between SARS-CoV-2 Spike and Human ACE2 Proteins Likely Requires Multiple High-Affinity Antibodies: An Immune Perspective

Blocking of the High-Affinity Interaction-Synapse Between SARS-CoV-2 Spike and Human ACE2 Proteins Likely Requires Multiple High-Affinity Antibodies: An Immune Perspective

The pandemic of Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2 has induced global eagerness to develop vaccines and therapeutics for treating COVID-19, including neutralizing antibodies. To develop effective therapeutic antibodies against SARS-CoV-2, it is critical to understand the intera...

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Bibliographic Details
Main Authors: Indu Khatri, Frank J. T. Staal, Jacques J. M. van Dongen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
ACE2
SARS-CoV
interaction-synapse
antibody
binding-affinity
felines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.570018/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.570018/full

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