Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative

Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative

Scutellarin (1) has been widely used to treat acute cerebral infarction in clinic, but poor aqueous solubility decreases its bioavailability. Interestingly, scutellarin (1) could be metabolized into scutellarein (2) in vivo. In this study, a sulfonic group was introduced at position C-8 of scutellar...

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Bibliographic Details
Main Authors: Ting Gu, Yue Zhong, Yu-Ting Lu, Ying Sun, Ze-Xi Dong, Wen-Yu Wu, Zhi-Hao Shi, Nian-Guang Li, Xin Xue, Fang Fang, He-Min Li, Yu-Ping Tang
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Molecules
Subjects:
scutellarin
scutellarein
sulfonated derivative
solubility
antioxidant
antithrombic
Online Access:http://www.mdpi.com/1420-3049/22/6/1028

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http://www.mdpi.com/1420-3049/22/6/1028

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