Learning time-varying information flow from single-cell epithelial to mesenchymal transition data.

Cellular regulatory networks are not static, but continuously reconfigure in response to stimuli via alterations in protein abundance and confirmation. However, typical computational approaches treat them as static interaction networks derived from a single time point. Here, we provide methods for l...

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Bibliographic Details
Main Authors: Smita Krishnaswamy, Nevena Zivanovic, Roshan Sharma, Dana Pe'er, Bernd Bodenmiller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0203389