Aggregation propensity of the human proteome.

Formation of amyloid-like fibrils is involved in numerous human protein deposition diseases, but is also an intrinsic property of polypeptide chains in general. Progress achieved recently now allows the aggregation propensity of proteins to be analyzed over large scales. In this work we used a previ...

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Bibliographic Details
Main Authors: Elodie Monsellier, Matteo Ramazzotti, Niccolò Taddei, Fabrizio Chiti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18927604/?tool=EBI