Self-Assembled Supramolecular Nanoparticles Improve the Cytotoxic Efficacy of CK2 Inhibitor THN7

Self-Assembled Supramolecular Nanoparticles Improve the Cytotoxic Efficacy of CK2 Inhibitor THN7

Since the approval of imatinib in 2001, kinase inhibitors have revolutionized cancer therapies. Inside this family of phosphotransferases, casein kinase 2 (CK2) is of great interest and numerous scaffolds have been investigated to design CK2 inhibitors. Recently, functionalized indeno[1,2-b]indoles...

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Bibliographic Details
Main Authors: Abdelhamid Nacereddine, Andre Bollacke, Eszter Róka, Christelle Marminon, Zouhair Bouaziz, Ferenc Fenyvesi, Ildikó Katalin Bácskay, Joachim Jose, Florent Perret, Marc Le Borgne
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Pharmaceuticals
Subjects:
indeno[1,2-b]indole
CK2 inhibitor
cyclodextrin
nanoparticles
in cellulo
human erythrocytes
A427 cells
Online Access:http://www.mdpi.com/1424-8247/11/1/10

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http://www.mdpi.com/1424-8247/11/1/10

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