Sulforaphane protects human umbilical vein cells against lipotoxicity by stimulating autophagy via an AMPK-mediated pathway

The protective role of sulforaphane (SFN) against saturated fatty acid (SFA)-induced lipotoxicity in human umbilical vein endothelium cell was determined. SFN protected endothelium cells against SFA-induced cell death. This protective activity was Nrf2-independent because silencing Nrf2 did not bloc...

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Bibliographic Details
Main Authors: Ning Wang, Juyang Zhao, Qian Liu, Xinping Diao, Baohua Kong
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615001243