Comparative Description of the Expression Profile of Interferon-Stimulated Genes in Multiple Cell Lineages Targeted by HIV-1 Infection

Comparative Description of the Expression Profile of Interferon-Stimulated Genes in Multiple Cell Lineages Targeted by HIV-1 Infection

Immediately after viral infections, innate immune sensors recognize viruses and lead to the production of type I interferon (IFN-I). IFN-I upregulates various genes, referred to as IFN-stimulated genes (ISGs), and some ISGs inhibit viral replication. HIV-1, the causative agent of AIDS, mainly infect...

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Bibliographic Details
Main Authors: Hirofumi Aso, Jumpei Ito, Yoshio Koyanagi, Kei Sato
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
interferon-stimulated gene
type I interferon
HIV-1
transcriptomics
evolution
bioinformatics
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00429/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00429/full

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