New insight into the role of MMP14 in metabolic balance

Membrane-anchored matrix metalloproteinase 14 (MMP14) is involved broadly in organ development through both its proteolytic and signal-transducing functions. Knockout of Mmp14 (KO) in mice results in a dramatic reduction of body size and wasting followed by premature death, the mechanism of which is...

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Bibliographic Details
Main Authors: Hidetoshi Mori, Ramray Bhat, Alexandre Bruni-Cardoso, Emily I. Chen, Danielle M. Jorgens, Kester Coutinho, Katherine Louie, Benjamin Ben Bowen, Jamie L. Inman, Victoria Tecca, Sarah J. Lee, Sabine Becker-Weimann, Trent Northen, Motoharu Seiki, Alexander D. Borowsky, Manfred Auer, Mina J. Bissell
Format: Article
Language:English
Published: PeerJ Inc. 2016-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2142.pdf