PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus

PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus

Long-term potentiation at hippocampal CA1 synapses can be due to increasing the number and/or single-channel conductance of AMPA receptors. The authors show that PKA and CaMKII are necessary and together sufficient to increase single channel conductance, via insertion of calcium-permeable AMPA recep...

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Bibliographic Details
Main Authors: Pojeong Park, John Georgiou, Thomas M. Sanderson, Kwang-Hee Ko, Heather Kang, Ji-il Kim, Clarrisa A. Bradley, Zuner A. Bortolotto, Min Zhuo, Bong-Kiun Kaang, Graham L. Collingridge
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20523-3

Internet

https://doi.org/10.1038/s41467-020-20523-3

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