Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates

Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates

Abstract Background Siglecs-11 and -16 are members of the sialic acid recognizing Ig-like lectin family, and expressed in same cells. Siglec-11 functions as an inhibitory receptor, whereas Siglec-16 exhibits activating properties. In humans, SIGLEC11 and SIGLEC16 gene sequences are extremely similar...

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Bibliographic Details
Main Authors: Toshiyuki Hayakawa, Zahra Khedri, Flavio Schwarz, Corinna Landig, Suh-Yuen Liang, Hai Yu, Xi Chen, Naoko T. Fujito, Yoko Satta, Ajit Varki, Takashi Angata
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Evolutionary Biology
Subjects:
Coevolution
Sialic acid
Paired receptors
Gene conversion
Primates
Online Access:http://link.springer.com/article/10.1186/s12862-017-1075-z

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http://link.springer.com/article/10.1186/s12862-017-1075-z

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