Cellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination.

BACKGROUND: The identification of Mycobacterium tuberculosis vaccines that elicit a protective immune response in the lungs is important for the development of an effective vaccine against tuberculosis. METHODS AND PRINCIPAL FINDINGS: In this study, a comparison of intranasal (i.n.) and subcutaneous...

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Main Authors: Suraj B Sable, Mani Cheruvu, Subhadra Nandakumar, Sunita Sharma, Kakali Bandyopadhyay, Kathryn L Kellar, James E Posey, Bonnie B Plikaytis, Rama Rao Amara, Thomas M Shinnick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3143185?pdf=render