Tau Fibril Formation in Cultured Cells Compatible with a Mouse Model of Tauopathy

Tau Fibril Formation in Cultured Cells Compatible with a Mouse Model of Tauopathy

Neurofibrillary tangles composed of hyperphosphorylated tau protein are primarily neuropathological features of a number of neurodegenerative diseases collectively termed tauopathy. To understand the mechanisms underlying the cause of tauopathy, precise cellular and animal models are required. Recen...

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Bibliographic Details
Main Authors: Gen Matsumoto, Kazuki Matsumoto, Taeko Kimura, Tetsuya Suhara, Makoto Higuchi, Naruhiko Sahara, Nozomu Mori
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:International Journal of Molecular Sciences
Subjects:
tauopathy
cellular model
sarkosyl insoluble tau
super-resolution microscopy
Online Access:http://www.mdpi.com/1422-0067/19/5/1497

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http://www.mdpi.com/1422-0067/19/5/1497

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