Linking hnRNP Function to ALS and FTD Pathology

Linking hnRNP Function to ALS and FTD Pathology

Following years of rapid progress identifying the genetic underpinnings of amyotrophic lateral sclerosis (ALS) and related diseases such as frontotemporal dementia (FTD), remarkable consistencies have emerged pointing to perturbed biology of heterogeneous nuclear ribonucleoproteins (hnRNPs) as a cen...

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Bibliographic Details
Main Authors: Maria D. Purice, J. Paul Taylor
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Neuroscience
Subjects:
amyotrophic lateral sclerosis
frontotemporal dementia
stress granules
hnRNPs
membraneless organelles
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2018.00326/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2018.00326/full

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