Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone

Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone

The spleen plays an important role in protective immunity to bloodborne pathogens. Macrophages and dendritic cells (DCs) in the spleen marginal zone capture microbial antigens to trigger adaptive immune responses. Marginal zone macrophages (MZMs) can also act as a replicative niche for intracellular...

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Bibliographic Details
Main Authors: Mohamed Habbeddine, Christophe Verthuy, Olivia Rastoin, Lionel Chasson, Magali Bebien, Marc Bajenoff, Sahil Adriouch, Joke M.M. den Haan, Josef M. Penninger, Toby Lawrence
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Cell Reports
Subjects:
NF-κB
dendritic cells
macrophages
inflammation
innate immunity
adaptive immunity
marginal zone
CD169
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717315917

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http://www.sciencedirect.com/science/article/pii/S2211124717315917

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