PAX7 Targets, CD54, Integrin α9β1, and SDC2, Allow Isolation of Human ESC/iPSC-Derived Myogenic Progenitors

PAX7 Targets, CD54, Integrin α9β1, and SDC2, Allow Isolation of Human ESC/iPSC-Derived Myogenic Progenitors

Pluripotent stem (PS)-cell-derived cell types hold promise for treating degenerative diseases. However, PS cell differentiation is intrinsically heterogeneous; therefore, clinical translation requires the development of practical methods for isolating progenitors from unwanted and potentially terato...

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Bibliographic Details
Main Authors: Alessandro Magli, Tania Incitti, James Kiley, Scott A. Swanson, Radbod Darabi, Fabrizio Rinaldi, Sridhar Selvaraj, Ami Yamamoto, Jakub Tolar, Ce Yuan, Ron Stewart, James A. Thomson, Rita C.R. Perlingeiro
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Subjects:
stem cell therapy
skeletal myogenesis
muscular dystrophy
RNA sequencing
muscle regeneration
ChIP sequencing
PAX7
CD54
integrin α9β1
SDC2
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717307830

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http://www.sciencedirect.com/science/article/pii/S2211124717307830

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