The Neuronal Overexpression of Gclc in Drosophila melanogaster Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax

The Neuronal Overexpression of Gclc in Drosophila melanogaster Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax

Some effects of aging in animals are tissue-specific. In D. melanogaster neuronal overexpression of Gclc increases lifespan and improves certain physiological parameters associated with health benefits such as locomotor activity, circadian rhythmicity, and stress resistance. Our previous transcripto...

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Bibliographic Details
Main Authors: Alexey Moskalev, Zulfiya Guvatova, Mikhail Shaposhnikov, Ekaterina Lashmanova, Ekaterina Proshkina, Liubov Koval, Alex Zhavoronkov, George Krasnov, Anna Kudryavtseva
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Genetics
Subjects:
Gclc
glutathione
lifespan
aging
gene expression
thorax
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00149/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00149/full

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