VENUS, a Novel Selection Approach to Improve the Accuracy of Neoantigens’ Prediction

VENUS, a Novel Selection Approach to Improve the Accuracy of Neoantigens’ Prediction

Neoantigens are tumor-specific antigens able to induce T-cell responses, generated by mutations in protein-coding regions of expressed genes. Previous studies demonstrated that only a limited subset of mutations generates neoantigens in microsatellite stable tumors. We developed a method, called VEN...

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Bibliographic Details
Main Authors: Guido Leoni, Anna Morena D’Alise, Fabio Giovanni Tucci, Elisa Micarelli, Irene Garzia, Maria De Lucia, Francesca Langone, Linda Nocchi, Gabriella Cotugno, Rosa Bartolomeo, Giuseppina Romano, Simona Allocca, Fulvia Troise, Alfredo Nicosia, Armin Lahm, Elisa Scarselli
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Vaccines
Subjects:
neoantigen
cancer vaccine
VENUS
prediction
MC38
Online Access:https://www.mdpi.com/2076-393X/9/8/880

Internet

https://www.mdpi.com/2076-393X/9/8/880

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