HIV-1 Vpr activates host CRL4-DCAF1 E3 ligase to degrade histone deacetylase SIRT7

by Xiaohong Zhou, Christina Monnie, Maria DeLucia, Jinwoo Ahn
Published 2021-03-01

HIV-1 Vpr Reprograms CLR4DCAF1 E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 Infection

by Junpeng Yan, Ming-Chieh Shun, Caili Hao, Yi Zhang, Juan Qian, Kasia Hrecka, Maria DeLucia, Christina Monnie, Jinwoo Ahn, Jacek Skowronski
Published 2018-10-01

Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of <i>Herpes Simplex</i> Oncolytic Virus

by Guendalina Froechlich, Carmen Caiazza, Chiara Gentile, Anna Morena D’Alise, Maria De Lucia, Francesca Langone, Guido Leoni, Gabriella Cotugno, Vittorio Scisciola, Alfredo Nicosia, Elisa Scarselli, Massimo Mallardo, Emanuele Sasso, Nicola Zambrano
Published 2020-11-01

Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment

by Maria De Lucia, Gabriella Cotugno, Veronica Bignone, Irene Garzia, Linda Nocchi, Francesca Langone, Biljana Petrovic, Emanuele Sasso, Simona Pepe, Guendalina Froechlich, Chiara Gentile, Nicola Zambrano, Gabriella Campadelli-Fiume, Alfredo Nicosia, Elisa Scarselli, Anna Morena D’Alise
Published 2020-12-01

VENUS, a Novel Selection Approach to Improve the Accuracy of Neoantigens’ Prediction

by Guido Leoni, Anna Morena D’Alise, Fabio Giovanni Tucci, Elisa Micarelli, Irene Garzia, Maria De Lucia, Francesca Langone, Linda Nocchi, Gabriella Cotugno, Rosa Bartolomeo, Giuseppina Romano, Simona Allocca, Fulvia Troise, Alfredo Nicosia, Armin Lahm, Elisa Scarselli
Published 2021-08-01

Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade

by Anna Morena D’Alise, Guido Leoni, Gabriella Cotugno, Fulvia Troise, Francesca Langone, Imma Fichera, Maria De Lucia, Lidia Avalle, Rosa Vitale, Adriano Leuzzi, Veronica Bignone, Elena Di Matteo, Fabio Giovanni Tucci, Valeria Poli, Armin Lahm, Maria Teresa Catanese, Antonella Folgori, Stefano Colloca, Alfredo Nicosia, Elisa Scarselli
Published 2019-06-01