Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli.

Antibiotic-resistant bacteria, particularly gram negative species, present significant health care challenges. The permeation of antibiotics through the outer membrane is largely effected by the porin superfamily, changes in which contribute to antibiotic resistance. A series of antibiotic resistant...

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Bibliographic Details
Main Authors: Hubing Lou, Min Chen, Susan S Black, Simon R Bushell, Matteo Ceccarelli, Tivadar Mach, Konstantinos Beis, Alison S Low, Victoria A Bamford, Ian R Booth, Hagan Bayley, James H Naismith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3203869?pdf=render