Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster

Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster

About two-thirds of the vital genes in the Drosophila genome are involved in eye development, making the fly eye an excellent genetic system to study cellular function and development, neurodevelopment/degeneration, and complex diseases such as cancer and diabetes. We developed a novel computational...

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Bibliographic Details
Main Authors: Janani Iyer, Qingyu Wang, Thanh Le, Lucilla Pizzo, Sebastian Grönke, Surendra S. Ambegaokar, Yuzuru Imai, Ashutosh Srivastava, Beatriz Llamusí Troisí, Graeme Mardon, Ruben Artero, George R. Jackson, Adrian M. Isaacs, Linda Partridge, Bingwei Lu, Justin P. Kumar, Santhosh Girirajan
Format: Article
Language:English
Published: Oxford University Press 2016-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
ommatidia
Drosophila melanogaster
neurodevelopmental disorders
modifier screens
rough eye
human disease models
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.027060

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http://g3journal.org/lookup/doi/10.1534/g3.116.027060

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