Iron accumulation in macrophages promotes the formation of foam cells and development of atherosclerosis

Iron accumulation in macrophages promotes the formation of foam cells and development of atherosclerosis

Abstract Background Macrophages that accumulate in atherosclerotic plaques contribute to progression of the lesions to more advanced and complex plaques. Although iron deposition was found in human atherosclerotic plaques, clinical and pre-clinical studies showed controversial results. Several epide...

Full description

Bibliographic Details
Main Authors: Jing Cai, Meng Zhang, Yutong Liu, Huihui Li, Longcheng Shang, Tianze Xu, Zhipeng Chen, Fudi Wang, Tong Qiao, Kuanyu Li
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cell & Bioscience
Subjects:
Atherosclerosis
Iron metabolism
Fpn1
Macrophages
Foam cell formation
Online Access:http://link.springer.com/article/10.1186/s13578-020-00500-5

Internet

http://link.springer.com/article/10.1186/s13578-020-00500-5

Similar Items