Enhanced regulatory sequence prediction using gapped k-mer features.

Oligomers of length k, or k-mers, are convenient and widely used features for modeling the properties and functions of DNA and protein sequences. However, k-mers suffer from the inherent limitation that if the parameter k is increased to resolve longer features, the probability of observing any spec...

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Bibliographic Details
Main Authors: Mahmoud Ghandi, Dongwon Lee, Morteza Mohammad-Noori, Michael A Beer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4102394?pdf=render