Transcription initiation activity sets replication origin efficiency in mammalian cells.

Transcription initiation activity sets replication origin efficiency in mammalian cells.

Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0.4% of the mouse genome with detailed molecular an...

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Bibliographic Details
Main Authors: Joana Sequeira-Mendes, Ramón Díaz-Uriarte, Anwyn Apedaile, Derek Huntley, Neil Brockdorff, María Gómez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2661365?pdf=render

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http://europepmc.org/articles/PMC2661365?pdf=render

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