Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes

LPL hydrolyzes triglycerides in triglyceride-rich lipoproteins along the capillaries of heart, skeletal muscle, and adipose tissue. The activity of LPL is repressed by angiopoietin-like 4 (ANGPTL4) but the underlying mechanisms have not been fully elucidated. Our objective was to study the cellular...

Full description

Bibliographic Details
Main Authors: Wieneke Dijk, Anne P. Beigneux, Mikael Larsson, André Bensadoun, Stephen G. Young, Sander Kersten
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520309342