The Effect of Citalopram on Genome-Wide DNA Methylation of Human Cells

Commonly used pharmaceutical drugs might alter the epigenetic state of cells, leading to varying degrees of long-term repercussions to human health. To test this hypothesis, we cultured HEK-293 cells in the presence of 50 μM citalopram, a common antidepressant, for 30 days and performed whole-genome...

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Bibliographic Details
Main Authors: Riya R. Kanherkar, Bruk Getachew, Joseph Ben-Sheetrit, Sudhir Varma, Thomas Heinbockel, Yousef Tizabi, Antonei B. Csoka
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2018/8929057