Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy
While infrared nanospectroscopy methods based on thermomechanical detection (AFM-IR) enables the acquisition of absorption spectra at the nanoscale, single molecule detection has not been possible so far. Here, the authors present off-resonance, low power and short pulse infrared nanospectroscopy (O...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-06-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-16728-1 |