Tau exhibits unique seeding properties in globular glial tauopathy

Tau exhibits unique seeding properties in globular glial tauopathy

Abstract Tauopathies are neurodegenerative disorders characterized by aggregation of microtubule associated tau protein in neurons and glia. They are clinically and pathologically heterogeneous depending on the isoform of tau protein that accumulates (three or four 31-to-32-amino-acid repeats [3R or...

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Bibliographic Details
Main Authors: Dah-eun Chloe Chung, Yari Carlomagno, Casey N. Cook, Karen Jansen-West, Lillian Daughrity, Laura J. Lewis-Tuffin, Monica Castanedes-Casey, Michael DeTure, Dennis W. Dickson, Leonard Petrucelli
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Acta Neuropathologica Communications
Subjects:
Tau
Tauopathy
Globular glial tauopathy
Seeding
Aggregation
Online Access:http://link.springer.com/article/10.1186/s40478-019-0691-9

Internet

http://link.springer.com/article/10.1186/s40478-019-0691-9

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