T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow

T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow

Long-lived plasma cells (PCs) in the bone marrow (BM) are a critical source of antibodies after infection or vaccination, but questions remain about the factors that control PCs. We found that systemic infection alters the BM, greatly reducing PCs and regulatory T (Treg) cells, a population that con...

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Bibliographic Details
Main Authors: Arielle Glatman Zaretsky, Christoph Konradt, Fabien Dépis, James B. Wing, Radhika Goenka, Daniela Gomez Atria, Jonathan S. Silver, Sunglim Cho, Amaya I. Wolf, William J. Quinn, Julie B. Engiles, Dorothy C. Brown, Daniel Beiting, Jan Erikson, David Allman, Michael P. Cancro, Shimon Sakaguchi, Li-Fan Lu, Christophe O. Benoist, Christopher A. Hunter
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
B cells
infectious disease
antibody
plasma cell
T regulatory cell
bone marrow
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717301377

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http://www.sciencedirect.com/science/article/pii/S2211124717301377

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