Computational screens can speed up the discovery of pharmaceutical cocrystals

by Rafel Prohens, Christopher A Hunter
Published 2018-12-01

Advances in understanding immunity to Toxoplasma gondii

by Elia D Tait, Christopher A Hunter
Published 2009-03-01

IL-21 is required for optimal antibody production and T cell responses during chronic Toxoplasma gondii infection.

by Jason S Stumhofer, Jonathan S Silver, Christopher A Hunter
Published 2013-01-01

Structural Fingerprints of Transcription Factor Binding Site Regions

by Peter Willett, Eleanor J. J. Gardiner, Christopher A. Hunter
Published 2009-03-01

Disruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assay.

by Jacqueline M Leung, Mark A Rould, Christoph Konradt, Christopher A Hunter, Gary E Ward
Published 2014-01-01

Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondii.

by Beth Gregg, Florence Dzierszinski, Elia Tait, Kimberly A Jordan, Christopher A Hunter, David S Roos
Published 2011-01-01

Heterogeneous CD8+ T cell migration in the lymph node in the absence of inflammation revealed by quantitative migration analysis.

by Edward J Banigan, Tajie H Harris, David A Christian, Christopher A Hunter, Andrea J Liu
Published 2015-02-01

The Group 3 Innate Lymphoid Cell Defect in Aryl Hydrocarbon Receptor Deficient Mice Is Associated with T Cell Hyperactivation during Intestinal Infection.

by Sagie Wagage, Gretchen Harms Pritchard, Lucas Dawson, Elizabeth L Buza, Gregory F Sonnenberg, Christopher A Hunter
Published 2015-01-01

Foxp4 is dispensable for T cell development, but required for robust recall responses.

by Karla R Wiehagen, Evann Corbo-Rodgers, Shanru Li, Elizabeth S Staub, Christopher A Hunter, Edward E Morrisey, Jonathan S Maltzman
Published 2012-01-01

Toxoplasma co-opts host cells it does not invade.

by Anita A Koshy, Hans K Dietrich, David A Christian, Jason H Melehani, Anjali J Shastri, Christopher A Hunter, John C Boothroyd
Published 2012-01-01

The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii.

by Daniel P Beiting, Shinya Hidano, Julie E Baggs, Jeanne M Geskes, Qun Fang, E John Wherry, Christopher A Hunter, David S Roos, Sara Cherry
Published 2015-07-01

Differential induction of TLR3-dependent innate immune signaling by closely related parasite species.

by Daniel P Beiting, Lucia Peixoto, Natalia S Akopyants, Stephen M Beverley, E John Wherry, David A Christian, Christopher A Hunter, Igor E Brodsky, David S Roos
Published 2014-01-01

Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus

by Keiko Rausch, Brent A. Hackett, Nathan L. Weinbren, Sophia M. Reeder, Yoel Sadovsky, Christopher A. Hunter, David C. Schultz, Carolyn B. Coyne, Sara Cherry
Published 2017-01-01

IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii

by Joseph T Clark, David A Christian, Jodi A Gullicksrud, Joseph A Perry, Jeongho Park, Maxime Jacquet, James C Tarrant, Enrico Radaelli, Jonathan Silver, Christopher A Hunter
Published 2021-04-01

Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii.

by Beena John, Tajie H Harris, Elia D Tait, Emma H Wilson, Beth Gregg, Lai Guan Ng, Paulus Mrass, David S Roos, Florence Dzierszinski, Wolfgang Weninger, Christopher A Hunter
Published 2009-07-01

B cells promote CD8 T cell primary and memory responses to subunit vaccines

by Jared Klarquist, Eric W. Cross, Scott B. Thompson, Benjamin Willett, Daniel L. Aldridge, Alayna K. Caffrey-Carr, Zhenming Xu, Christopher A. Hunter, Andrew Getahun, Ross M. Kedl
Published 2021-08-01

IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals.

by Ana Villegas-Mendez, J Brian de Souza, Seen-Wai Lavelle, Emily Gwyer Findlay, Tovah N Shaw, Nico van Rooijen, Christiaan J Saris, Christopher A Hunter, Eleanor M Riley, Kevin N Couper
Published 2013-01-01

IFNγ signaling endows DCs with the capacity to control type I inflammation during parasitic infection through promoting T-bet+ regulatory T cells.

by Hyang-Mi Lee, Anne Fleige, Ruth Forman, Sunglim Cho, Aly Azeem Khan, Ling-Li Lin, Duc T Nguyen, Aisling O'Hara-Hall, Zhinan Yin, Christopher A Hunter, Werner Muller, Li-Fan Lu
Published 2015-02-01

Analysis of behavior and trafficking of dendritic cells within the brain during toxoplasmic encephalitis.

by Beena John, Brendon Ricart, Elia D Tait Wojno, Tajie H Harris, Louise M Randall, David A Christian, Beth Gregg, Daniel Manzoni De Almeida, Wolfgang Weninger, Daniel A Hammer, Christopher A Hunter
Published 2011-09-01

Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.

by Christopher D Dupont, David A Christian, Elizabeth M Selleck, Marion Pepper, Michael Leney-Greene, Gretchen Harms Pritchard, Anita A Koshy, Sagie Wagage, Morgan A Reuter, L David Sibley, Michael R Betts, Christopher A Hunter
Published 2014-04-01