Exploration of Blood Lipoprotein and Lipid Fraction Profiles in Healthy Subjects through Integrated Univariate, Multivariate, and Network Analysis Reveals Association of Lipase Activity and Cholesterol Esterification with Sex and Age

Exploration of Blood Lipoprotein and Lipid Fraction Profiles in Healthy Subjects through Integrated Univariate, Multivariate, and Network Analysis Reveals Association of Lipase Activity and Cholesterol Esterification with Sex and Age

In this study, we investigated blood lipoprotein and lipid fraction profiles, quantified using nuclear magnetic resonance, in a cohort of 844 healthy blood donors, integrating standard univariate and multivariate analysis with predictive modeling and network analysis. We observed a strong associatio...

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Bibliographic Details
Main Authors: Yasmijn Balder, Alessia Vignoli, Leonardo Tenori, Claudio Luchinat, Edoardo Saccenti
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Metabolites
Subjects:
analysis of biological networks
lipid metabolism
lipidomics
metabolomics
nuclear magnetic resonance
Online Access:https://www.mdpi.com/2218-1989/11/5/326

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https://www.mdpi.com/2218-1989/11/5/326

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