Automated analysis of NF-κB nuclear translocation kinetics in high-throughput screening.

Automated analysis of NF-κB nuclear translocation kinetics in high-throughput screening.

Nuclear entry and exit of the NF-κB family of dimeric transcription factors plays an essential role in regulating cellular responses to inflammatory stress. The dynamics of this nuclear translocation can vary significantly within a cell population and may dramatically change e.g. upon drug exposure....

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Bibliographic Details
Main Authors: Zi Di, Bram Herpers, Lisa Fredriksson, Kuan Yan, Bob van de Water, Fons J Verbeek, John H N Meerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3531459?pdf=render

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http://europepmc.org/articles/PMC3531459?pdf=render

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