Neuroserpin Inclusion Bodies in a FENIB Yeast Model

Neuroserpin Inclusion Bodies in a FENIB Yeast Model

FENIB (familial encephalopathy with neuroserpin inclusion bodies) is a human monogenic disease caused by point mutations in the <i>SERPINI1</i> gene, characterized by the intracellular deposition of polymers of neuroserpin (NS), which leads to proteotoxicity and cell death. Despite the d...

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Bibliographic Details
Main Authors: Valentina Vapore, Corrado Mazzaglia, Diego Sibilia, Mara Del Vecchio, Gernot Fruhmann, Marta Valenti, Elena Miranda, Teresa Rinaldi, Joris Winderickx, Cristina Mazzoni
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Microorganisms
Subjects:
yeast
neurodegeneration
FENIB
protein aggregation
Online Access:https://www.mdpi.com/2076-2607/9/7/1498

Internet

https://www.mdpi.com/2076-2607/9/7/1498

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