Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice

Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice

Abstract Background Antibiotic exposure alters the microbiota, which can impact the inflammatory immune responses. Critically ill patients frequently receive antibiotic treatment and are often subjected to mechanical ventilation, which may induce local and systemic inflammatory responses and develop...

Full description

Bibliographic Details
Main Authors: Sandra-Maria Wienhold, Mario Macrì, Geraldine Nouailles, Kristina Dietert, Corinne Gurtner, Achim D Gruber, Markus M Heimesaat, Jasmin Lienau, Fabian Schumacher, Burkhard Kleuser, Bastian Opitz, Norbert Suttorp, Martin Witzenrath, Holger C Müller-Redetzky
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Critical Care
Subjects:
Broad-spectrum antibiotic therapy
Ventilator-induced lung injury
Microbiota
Online Access:http://link.springer.com/article/10.1186/s13054-018-2213-8

Internet

http://link.springer.com/article/10.1186/s13054-018-2213-8

Similar Items