The Genome Sequence of the Eastern Woodchuck (Marmota monax) – A Preclinical Animal Model for Chronic Hepatitis B

The Genome Sequence of the Eastern Woodchuck (Marmota monax) – A Preclinical Animal Model for Chronic Hepatitis B

The Eastern woodchuck (Marmota monax) has been extensively used in research of chronic hepatitis B and liver cancer because its infection with the woodchuck hepatitis virus closely resembles a human hepatitis B virus infection. Development of novel immunotherapeutic approaches requires genetic infor...

Full description

Bibliographic Details
Main Authors: Tyler S. Alioto, Fernando Cruz, Jèssica Gómez-Garrido, Miriam Triyatni, Marta Gut, Leonor Frias, Anna Esteve-Codina, Stephan Menne, Anna Kiialainen, Nadine Kumpesa, Fabian Birzele, Roland Schmucki, Ivo G. Gut, Olivia Spleiss
Format: Article
Language:English
Published: Oxford University Press 2019-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
eastern woodchuck
marmota monax
chronic hepatitis b
hepatocellular carcinoma
immune response
whole genome sequencing
genome assembly
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400413

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400413

Similar Items