Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency.
A critical determinant in chronic gammaherpesvirus infections is the ability of these viruses to establish latency in a lymphocyte reservoir. The nuclear factor (NF)-kappaB family of transcription factors represent key players in B-cell biology and are targeted by gammaherpesviruses to promote host...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-01-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC1781481?pdf=render |