Highly specific and ultrasensitive plasma test detects Abeta(1–42) and Abeta(1–40) in Alzheimer’s disease

Highly specific and ultrasensitive plasma test detects Abeta(1–42) and Abeta(1–40) in Alzheimer’s disease

Abstract Plasma biomarkers that reflect specific amyloid beta (Abeta) proteoforms provide an insight in the treatment effects of Alzheimer’s disease (AD) therapies. Our aim was to develop and validate ready-to-use Simoa ‘Amyblood’ assays that measure full length Abeta1-42 and Abeta1-40 and compare t...

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Bibliographic Details
Main Authors: Elisabeth H. Thijssen, Inge M. W. Verberk, Jeroen Vanbrabant, Anne Koelewijn, Hans Heijst, Philip Scheltens, Wiesje van der Flier, Hugo Vanderstichele, Erik Stoops, Charlotte E. Teunissen
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89004-x

Internet

https://doi.org/10.1038/s41598-021-89004-x

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