Chronic dietary n-6 PUFA deprivation leads to conservation of arachidonic acid and more rapid loss of DHA in rat brain phospholipids[S]

Chronic dietary n-6 PUFA deprivation leads to conservation of arachidonic acid and more rapid loss of DHA in rat brain phospholipids[S]

To determine how the level of dietary n-6 PUFA affects the rate of loss of arachidonic acid (ARA) and DHA in brain phospholipids, male rats were fed either a deprived or adequate n-6 PUFA diet for 15 weeks postweaning, and then subjected to an intracerebroventricular infusion of 3H-ARA or 3H-DHA. Br...

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Bibliographic Details
Main Authors: Lauren E. Lin, Chuck T. Chen, Kayla D. Hildebrand, Zhen Liu, Kathryn E. Hopperton, Richard P. Bazinet
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Journal of Lipid Research
Subjects:
polyunsaturated fatty acid
docosahexaenoic acid
kinetics
metabolism
eicosanoid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520356236

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520356236

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