Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome

Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome

Abstract Background The gut microbiome and iron status are known to play a role in the pathophysiology of non-alcoholic fatty liver disease (NAFLD), although their complex interaction remains unclear. Results Here, we applied an integrative systems medicine approach (faecal metagenomics, plasma and...

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Main Authors: Jordi Mayneris-Perxachs, Marina Cardellini, Lesley Hoyles, Jèssica Latorre, Francesca Davato, José Maria Moreno-Navarrete, María Arnoriaga-Rodríguez, Matteo Serino, James Abbott, Richard H. Barton, Josep Puig, Xavier Fernández-Real, Wifredo Ricart, Christopher Tomlinson, Mark Woodbridge, Paolo Gentileschi, Sarah A. Butcher, Elaine Holmes, Jeremy K. Nicholson, Vicente Pérez-Brocal, Andrés Moya, Donald Mc Clain, Rémy Burcelin, Marc-Emmanuel Dumas, Massimo Federici, José-Manuel Fernández-Real
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Microbiome
Subjects:
Systems medicine
Ferritin
Iron status
Gut microbiome
Non-alcoholic fatty liver disease
Shotgun sequencing
Online Access:https://doi.org/10.1186/s40168-021-01052-7

Internet

https://doi.org/10.1186/s40168-021-01052-7

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