Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale

by David William Randall, Julius Kieswich, Jonathan Swann, Kieran McCafferty, Christoph Thiemermann, Michael Curtis, Lesley Hoyles, Muhammed Magdi Yaqoob
Published 2019-09-01

Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier

by Lesley Hoyles, Tom Snelling, Umm-Kulthum Umlai, Jeremy K. Nicholson, Simon R. Carding, Robert C. Glen, Simon McArthur
Published 2018-03-01

Succession of Bifidobacterium longum Strains in Response to a Changing Early Life Nutritional Environment Reveals Dietary Substrate Adaptations

by Magdalena Kujawska, Sabina Leanti La Rosa, Laure C. Roger, Phillip B. Pope, Lesley Hoyles, Anne L. McCartney, Lindsay J. Hall
Published 2020-08-01

Klebsiella pneumoniae subsp. pneumoniae–bacteriophage combination from the caecal effluent of a healthy woman

by Lesley Hoyles, James Murphy, Horst Neve, Knut J. Heller, Jane F. Turton, Jennifer Mahony, Jeremy D. Sanderson, Barry Hudspith, Glenn R. Gibson, Anne L. McCartney, Douwe van Sinderen
Published 2015-07-01

Genome Characterization of a Novel Wastewater Bacteroides fragilis Bacteriophage (vB_BfrS_23) and its Host GB124

by Mohammad A. Tariq, Fiona Newberry, Fiona Newberry, Rik Haagmans, Rik Haagmans, Catherine Booth, Tom Wileman, Tom Wileman, Lesley Hoyles, Martha R. J. Clokie, James Ebdon, Simon R. Carding, Simon R. Carding
Published 2020-10-01

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota

by Lesley Hoyles, Maria L. Jiménez-Pranteda, Julien Chilloux, Francois Brial, Antonis Myridakis, Thomas Aranias, Christophe Magnan, Glenn R. Gibson, Jeremy D. Sanderson, Jeremy K. Nicholson, Dominique Gauguier, Anne L. McCartney, Marc-Emmanuel Dumas
Published 2018-04-01

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

by Marc-Emmanuel Dumas, Alice R. Rothwell, Lesley Hoyles, Thomas Aranias, Julien Chilloux, Sophie Calderari, Elisa M. Noll, Noémie Péan, Claire L. Boulangé, Christine Blancher, Richard H. Barton, Quan Gu, Jane F. Fearnside, Chloé Deshayes, Christophe Hue, James Scott, Jeremy K. Nicholson, Dominique Gauguier
Published 2017-07-01

Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in youn...

by Alfonsina D’Amato, Lorenzo Di Cesare Mannelli, Elena Lucarini, Angela L. Man, Gwenaelle Le Gall, Jacopo J. V. Branca, Carla Ghelardini, Amedeo Amedei, Eugenio Bertelli, Mari Regoli, Alessandra Pacini, Giulia Luciani, Pasquale Gallina, Annalisa Altera, Arjan Narbad, Massimo Gulisano, Lesley Hoyles, David Vauzour, Claudio Nicoletti
Published 2020-10-01

A Data Integration Multi-Omics Approach to Study Calorie Restriction-Induced Changes in Insulin Sensitivity

by Maria Carlota Dao, Nataliya Sokolovska, Rémi Brazeilles, Séverine Affeldt, Véronique Pelloux, Edi Prifti, Edi Prifti, Julien Chilloux, Eric O. Verger, Brandon D. Kayser, Judith Aron-Wisnewsky, Judith Aron-Wisnewsky, Farid Ichou, Estelle Pujos-Guillot, Lesley Hoyles, Lesley Hoyles, Catherine Juste, Joël Doré, Marc-Emmanuel Dumas, Salwa W. Rizkalla, Bridget A. Holmes, Jean-Daniel Zucker, Jean-Daniel Zucker, Karine Clément, Karine Clément, The MICRO-Obes Consortium, Aurélie Cotillard, Sean P. Kennedy, Nicolas Pons, Emmanuelle Le Chatelier, Mathieu Almeida, Benoit Quinquis, Nathalie Galleron, Jean-Michel Batto, Pierre Renault, Stanislav Dusko Ehrlich, Hervé Blottière, Marion Leclerc, Tomas de Wouters, Patricia Lepage
Published 2019-02-01

Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

by Lydia Durant, Régis Stentz, Alistair Noble, Johanne Brooks, Nadezhda Gicheva, Durga Reddi, Matthew J. O’Connor, Lesley Hoyles, Anne L. McCartney, Ripple Man, E. Tobias Pring, Stella Dilke, Philip Hendy, Jonathan P. Segal, Dennis N. F. Lim, Ravi Misra, Ailsa L. Hart, Naila Arebi, Simon R. Carding, Stella C. Knight
Published 2020-06-01

Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome

by Jordi Mayneris-Perxachs, Marina Cardellini, Lesley Hoyles, Jèssica Latorre, Francesca Davato, José Maria Moreno-Navarrete, María Arnoriaga-Rodríguez, Matteo Serino, James Abbott, Richard H. Barton, Josep Puig, Xavier Fernández-Real, Wifredo Ricart, Christopher Tomlinson, Mark Woodbridge, Paolo Gentileschi, Sarah A. Butcher, Elaine Holmes, Jeremy K. Nicholson, Vicente Pérez-Brocal, Andrés Moya, Donald Mc Clain, Rémy Burcelin, Marc-Emmanuel Dumas, Massimo Federici, José-Manuel Fernández-Real
Published 2021-05-01