Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

Although Capicua (Cic), a transcriptional repressor, is linked to cancer, little is known about its function in the non-diseased brain. Here, authors show that Cic is strongly expressed in astrocytic and neuronal lineage cells during development and regulates proliferation and lineage selection via...

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Bibliographic Details
Main Authors: Shiekh Tanveer Ahmad, Alexandra D. Rogers, Myra J. Chen, Rajiv Dixit, Lata Adnani, Luke S. Frankiw, Samuel O. Lawn, Michael D. Blough, Mana Alshehri, Wei Wu, Marco A. Marra, Stephen M. Robbins, J. Gregory Cairncross, Carol Schuurmans, Jennifer A. Chan
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09949-6

Internet

https://doi.org/10.1038/s41467-019-09949-6

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