Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors
Although Capicua (Cic), a transcriptional repressor, is linked to cancer, little is known about its function in the non-diseased brain. Here, authors show that Cic is strongly expressed in astrocytic and neuronal lineage cells during development and regulates proliferation and lineage selection via...
Main Authors: | , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-05-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-09949-6 |