A new class of multimerization selective inhibitors of HIV-1 integrase.
The quinoline-based allosteric HIV-1 integrase (IN) inhibitors (ALLINIs) are promising candidates for clinically useful antiviral agents. Studies using these compounds have highlighted the role of IN in both early and late stages of virus replication. However, dissecting the exact mechanism of actio...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-05-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4038613?pdf=render |