Antigen receptor control of methionine metabolism in T cells
Immune activated T lymphocytes modulate the activity of key metabolic pathways to support the transcriptional reprograming and reshaping of cell proteomes that permits effector T cell differentiation. The present study uses high resolution mass spectrometry and metabolic labelling to explore how mur...
Main Authors: | Linda V Sinclair, Andrew JM Howden, Alejandro Brenes, Laura Spinelli, Jens L Hukelmann, Andrew N Macintyre, Xiaojing Liu, Sarah Thomson, Peter M Taylor, Jeffrey C Rathmell, Jason W Locasale, Angus I Lamond, Doreen A Cantrell |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/44210 |
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