Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons.

Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons.

Some pathological conditions with feeding pattern alterations, including obesity and Huntington disease (HD) are associated with hypothalamic dysfunction and neuronal cell death. Additionally, the hypothalamus is a neurogenic region with the constitutive capacity to generate new cells of neuronal li...

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Bibliographic Details
Main Authors: Lígia Sousa-Ferreira, Ana Rita Álvaro, Célia Aveleira, Magda Santana, Inês Brandão, Sebastian Kügler, Luís Pereira de Almeida, Cláudia Cavadas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3092771?pdf=render

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http://europepmc.org/articles/PMC3092771?pdf=render

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